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| congenital nephrotic syndrome ： ウィキペディア英語版 |
congenital nephrotic syndrome
Congenital nephrotic syndrome is an inherited disorder characterized by protein in the urine and swelling of the body.
==Causes==
Congenital nephrotic syndrome is a very rare form of nephrotic syndrome. It occurs predominantly in families of Finnish origin and manifests shortly after birth. It is an inherited disorder. The condition is caused by a defect in the protein nephrin, which is found in the kidney.
Proteins and fats are excreted in the urine, and there is an abnormally high fat level in the blood. Swelling occurs due to kidney failure, combined with the loss of blood protein. This is because proteins in the blood normally keep fluids in the blood stream, and when protein level is low, the fluid can leak into the body tissues.
Some of the proteins lost in the urine are immune system antibodies that fight infections. The disorder commonly results in infection, malnutrition, and kidney failure.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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